Joe Hoffman made this clock in the shape of a single coil stratocaster pickup . Six nixie vacuum tubes display the time, where the pickup's magnets would be.
The top and bottom of the pickup-clock were cut out of stainless steel by the Big Blue Saw Company. You send them a design and they will cut it out using their CNC waterjet and send it back to you.
This project by John Williams shows how you can make a guitar neck using a home-built CNC machine. John built the CNC machine with plans and a kit from HobbyCNC.com. (Check out www.cnczone.com for free plans). The software used was: Rhino 3D to design the neck, MeshCAM to generate the tool paths for the maching process and TurboCNC to operate the machine.
This project describes how to make a CNC (computer numerical control) machine that could be used to make guitar parts. CNC may not always be the most efficient way to make guitar parts (a band saw and pin router is often the most sensible way to do guitar woodwork) but they are a flexible way to convert complicated 3D computer designs into reality. A good discussion about the role of CNC in guitar making was posted over at project guitar .