The Gibson Duane Eddy Signature model was introduced in 2004 by the Gibson's Custom, Art & Historic division - marking Eddy's 50 years in the music business. The Duane Eddy Signature model had a highly figured maple top, back and sides. The body had the familiar shape of Gibson's classic L-5 model, with a rounded "Venetian" cutaway horn, but at 16 inches wide, it was an inch smaller than the L-5. The two single-coil pickups were custom-designed to Eddy's specs by pickup guru Seymour Duncan. An additional L.R. Baggs transducer pickup in the bridge provided pure acoustic tone. The custom-designed controls allowed the guitar to be played with a blend of the transducer and magnetic pickups. The bridge pickup tone knob was push/pull to activate and blend the L.R. Baggs - when, pulled upward, engages the L.R. Baggs volume control, which can be blended with the magnetic pickup volumes. So this instrument actually has 4 volume controls and 2 tone controls. Other unique appointments were a maple/walnut slim neck with ebony fingerboard, pearl "moustache" fingerboard inlays, "Duane Eddy" engraved pickguard, nickel-plated hardware and a Bigsby vibrola tailpiece. The guitar came in rockabilly brown finish only.

Eddy was the first rock and roll guitarist ever to have a signature model guitar. In 1961 Guild Guitars introduced the Duane Eddy Models DE-400 and the deluxe DE-500.